Aging: One Thing Leads to Another

نویسندگان

  • Marion Schmidt
  • Brian K. Kennedy
چکیده

Mitochondria deteriorate during the aging process, but the underlying mechanisms for the decline of this critical organelle are unknown. A new study indicates that in yeast an age-dependent reduction in vacuolar acidification leads to mitochondrial dysfunction through a surprising mechanism: loss of vacuolar neutral amino acid transport.

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عنوان ژورنال:
  • Current Biology

دوره 22  شماره 

صفحات  -

تاریخ انتشار 2012